Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity related to bortezomib, a proteasome inhibitor Employed in the treatment of multiple myeloma. Its synthesis or review is important for guaranteeing the purity and security of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound while in the synthesis of imatinib, a drug that targets particular kinds of most cancers, which includes chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates within the synthesis of gemcitabine, an anti-cancer drug. Their analyze is vital for optimizing the production approach and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist used in the therapy of breast most cancers. Many intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug efficient in treating cancers which include ovarian, breast, and lung most cancers.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the treatment of colorectal most cancers and modest cell lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is linked to the synthesis of adamantane derivatives, which have numerous purposes, which include antiviral Homes.
Vildagliptin Intermediates: Used in 17-(3-pyridinyl)- the creation of vildagliptin, an oral drug for variety 2 diabetic issues that inhibits the enzyme DPP-4 to manage blood sugar ranges.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved in the synthesis of varied gluconic acid derivatives, which can be Employed in foodstuff, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor in the synthesis of canagliflozin, a medication applied to handle style 3-Amino-1-hydroxyadamantane 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).